EXTRACORPOREAL PREGNANCY
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Artificial Wombs |
The option of getting a child from an artificial womb, as opposed to the traditional way, has great advantages. Pregnancies are very demanding, causing all manners of severe physical discomfort and often cause ugly deformations. These are common symptoms of a pregnancy according to the wiki page: tiredness, constipation, pelvic girdle pain, back pain, Braxton Hicks contractions, edema, increased urinary frequency, urinary tract infection, varicose veins, haemorrhoids, regurgitation, heartburn, nausea, and stretch marks. And that's only the regular stuff. There is also a chance of all manners of dangerous and painful complications. In rare occasions childbirth can even lead to the death of the mother.
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Incubator |
Also important is the fact that inside the artificial womb, the baby can be monitored 24/7. If anything bad happens we can respond quickly. We can design the artificial womb so that the baby is very accessible to doctors. And if the baby sustains irreversible damage, we will notice that, and can easily abort the pregnancy without spending a lot of time and money to find out at birth that the child has only half a brain. We also reduce the possibility that the mother becomes too attached to the unfinished person, and decides to keep it.
No longer will the mother's diet be a problem for the child. Normally if the mother consumes a lot of alcohol, the baby will suffer from a fetal alcohol spectrum disorder, which includes serious brain defects (ref). Malnutrition might also cause negative epigenetic changes in the baby (ref).
We know that the unborn child can learn things, like language basics, and taste preference. With the artificial wombs you can highly regulate what you want the child to learn. This can be done automatically, and with involvement of the parents.
We know that the unborn child can learn things, like language basics, and taste preference. With the artificial wombs you can highly regulate what you want the child to learn. This can be done automatically, and with involvement of the parents.
If these advantages weren't enough, there are even more things that will greatly improve our future society.
EUGENICS
Let's first get the nasty things out of the way. Eugenics has a very bad name, mainly due to practices starting in the early 1900s to 1945. People at that time had extremely simplistic ideas about heredity, and even about modern society. People thought, for instance, that criminal behaviour and poverty were both strongly genetically determined. If you just prevent criminals and poor people to reproduce, you create a 'race' with only lawful, rich people. Everybody happy, <ahem>. And don't think that the 'evil' German Nazis were the only ones involved in this. It was a common practice in the whole of the civilized world. Civilized indeed. People that were thought to carry genes that benefited society were encouraged to reproduce, and people with 'bad blood' were discouraged (this sometimes included sterilization, incarceration, or murder).
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Transhumanism Logo |
I certainly do not advocate sterilization of certain people that happen to have genetic defects. No, that would be unfair (they are punished without having committed a crime) and unequal (people ought to have equal rights).
When we have created human artificial breeding centres around the world, we ought to sterilize all human beings.
GENOME BUILDING
Scientists are able to synthesize chromosomes artificially, though it's difficult to create long chromosomes like those of humans. I expect a quick evolution of DNA synthesizing techniques, because it's so useful for molecular biologists. Think about how fast sequencing techniques have changed. When synthesizing large chromosomes becomes commonplace, genetic manipulation will be so much faster and easier.
Each human being has two sets of chromosomes in their somatic cells, and therefore two copies of each (autosomal) gene. These copies are called alleles, and are rarely completely the same. One human being only has two (different) alleles of a specific gene, but in a population many different alleles exist. Differences between alleles may have (almost) no effect on a person's phenotype. Some alleles, however, have a significant negative effect. If there's an error in a critical component of a gene's promoter, the protein might not be produced. Changes in the coding region might alter the shape of the gene product into a dysfunctional protein, or even a highly toxic one. Variants that improve the functioning of a gene are also possible. For example, the allele CCR5-Δ32 provides 100% protection against HIV-1. Some MSTN alleles strongly increase muscularity, and consequently increase physical strength.
Sorting out all variants of all genes is an extremely laborious task. We possess about 25.000 (protein-coding) genes, and hundreds or thousands of alleles can exist per gene. Some differences between alleles may not matter, but some do. Therefore we need a good computer with software that chooses among alleles, and assembles the genomes.
Some alleles give 100% chance of a specific disease. Such alleles need to be absent from all artificial genomes. However, most alleles will only provide a certain chance of getting a certain disease (or certain benefits). For example, oncogenes increase the likelihood of getting cancer. Cancer requires X specific mutations in one particular cell, but with 1 oncogene that number becomes X-1. Other alleles may even be less clearly associated with a disease, just because we do not yet know all the details of every process in our bodies. That's why we need the program to work with chances of 'inheritance'.
We can study a group of humans with the same disease and a group of otherwise similar humans without that disease, and inspect the genetic code. One particular variation in a gene might be present in 80% of those diseased people, and in 30% of non-diseased people. If this difference is significant, the computer should decrease the chance of selecting that particular allele. But because it's not 100%/ 0%, that chance should not be 0. That's because a correlation is not the same as a causal relation. And we do not want to remove all variability from our genomes. We wouldn't want to create identical clones.
Studies for positive traits can be performed too. You can do IQ tests, for instance, and link the result of those tests to the genetic variation. The higher the linkage between a particular sequence and a positive result on the test, the higher the chance should be of getting that piece into the artificial genome.
After we have tested lots of people for all manners of traits, we will probably find that some alleles have a positive effect on one trait, and a negative effect on another. We need to provide some mechanism for the computer to choose which trait is preferred over which other. For this I can imagine we give our future parents a questionnaire with questions about their future child. Each question compares two traits, and the parents have to decide which they deem more important. When they're done we can give that information to the computer, and the computer can do its magic.
Perhaps we can even allow a neutral option, which the computer interprets as choosing the one or the other at random.
BIRTH CONTROL
Did I mention mandatory sterilization somewhere? Yes I did. Well, in the first of the solutions you do have two options. You either choose to get medical care from your government with sterilization, or no sterilization and no medical care. That'll make most of the people enthusiastic about sterilization :P. Or perhaps not. It'll only work in developed, western countries. And only when you've educated the people about it. And when the choice has been made democratically. Especially Islamic countries will be strongly opposed no matter what you'll tell them. Every time you produce a vaccine against some dreadful disease for free, ignorant Muslims see it as part of some grand conspiracy by Amereeka and other nations to sterilize them. Perhaps it's better if we design a virus that sterilizes everybody. The 'pathogen' spreads, all will get mild flu-like symptoms, and only after a while will they find out that they cannot get kids anymore.
Of course, we should only do this when we already have birth centres around the world. And when the world is ready for such an intervention. We do not want to cause a third world war, or create total anarchy.
Oh, God why on earth do you want to sterilize everybody? Are you thinking this? Well, the answer is that I think it's very beneficial to society, and the individual, that the size of the population is highly controlled. Big fluctuations cause problems with supply and demand. If the population size shrinks, there aren't enough teachers, and doctors, etc. If the population explodes, society suffers from unemployment and resource shortages. If the population size is constant, or if the growth rate is constant, we can much better anticipate what the resource demand and worker supply is going to be. We can adjust the number of houses we build, and we can provide better vocational counselling.
There are other advantages too. Crime often stems from some trauma during childhood. Raising a child is very important and should not be taken lightly. Therefore, I propose we get mandatory parenting courses. The first course and exam are free. If you fail the exam, you have to pay for subsequent courses and exams. This will prevent some accidents for uneducated but otherwise good parents, and prevents bad people from abusing their children. Not only should we get tests, we also should check whether the parents can support their children. Do they have a job? Own a house? If either of these questions is 'no', they should not be allowed to get a child until they do. Again, this is to ensure child welfare. Thirdly, we should check for their criminal background. Some past offences like (child) rape and murder are not very compatible with proper parenting, in my opinion. Such people are also excluded.
Of course I'm not saying we will prevent all child-abuse this way. But it will help a lot. I do want that the procedure is standardized, and all decisions accessible, so that we don't create powerful bureaucrats.
FINAL REMARKS
First, I want to say that without the sterilization part, the artificial human breeding is still a good idea. We'll get healthier and smarter people, which is a big thing already. And with proper education human population growth is already reduced a lot. And before we can control human population growth, we need societies that are designed to minimize corruption. Baby breeding should not become a big money-making business. The current world is not ready for it yet.
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Human Chromosomes |
Some alleles give 100% chance of a specific disease. Such alleles need to be absent from all artificial genomes. However, most alleles will only provide a certain chance of getting a certain disease (or certain benefits). For example, oncogenes increase the likelihood of getting cancer. Cancer requires X specific mutations in one particular cell, but with 1 oncogene that number becomes X-1. Other alleles may even be less clearly associated with a disease, just because we do not yet know all the details of every process in our bodies. That's why we need the program to work with chances of 'inheritance'.
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Piece of genetic code |
Studies for positive traits can be performed too. You can do IQ tests, for instance, and link the result of those tests to the genetic variation. The higher the linkage between a particular sequence and a positive result on the test, the higher the chance should be of getting that piece into the artificial genome.
After we have tested lots of people for all manners of traits, we will probably find that some alleles have a positive effect on one trait, and a negative effect on another. We need to provide some mechanism for the computer to choose which trait is preferred over which other. For this I can imagine we give our future parents a questionnaire with questions about their future child. Each question compares two traits, and the parents have to decide which they deem more important. When they're done we can give that information to the computer, and the computer can do its magic.
Perhaps we can even allow a neutral option, which the computer interprets as choosing the one or the other at random.
BIRTH CONTROL
Did I mention mandatory sterilization somewhere? Yes I did. Well, in the first of the solutions you do have two options. You either choose to get medical care from your government with sterilization, or no sterilization and no medical care. That'll make most of the people enthusiastic about sterilization :P. Or perhaps not. It'll only work in developed, western countries. And only when you've educated the people about it. And when the choice has been made democratically. Especially Islamic countries will be strongly opposed no matter what you'll tell them. Every time you produce a vaccine against some dreadful disease for free, ignorant Muslims see it as part of some grand conspiracy by Amereeka and other nations to sterilize them. Perhaps it's better if we design a virus that sterilizes everybody. The 'pathogen' spreads, all will get mild flu-like symptoms, and only after a while will they find out that they cannot get kids anymore.
Of course, we should only do this when we already have birth centres around the world. And when the world is ready for such an intervention. We do not want to cause a third world war, or create total anarchy.
Oh, God why on earth do you want to sterilize everybody? Are you thinking this? Well, the answer is that I think it's very beneficial to society, and the individual, that the size of the population is highly controlled. Big fluctuations cause problems with supply and demand. If the population size shrinks, there aren't enough teachers, and doctors, etc. If the population explodes, society suffers from unemployment and resource shortages. If the population size is constant, or if the growth rate is constant, we can much better anticipate what the resource demand and worker supply is going to be. We can adjust the number of houses we build, and we can provide better vocational counselling.
There are other advantages too. Crime often stems from some trauma during childhood. Raising a child is very important and should not be taken lightly. Therefore, I propose we get mandatory parenting courses. The first course and exam are free. If you fail the exam, you have to pay for subsequent courses and exams. This will prevent some accidents for uneducated but otherwise good parents, and prevents bad people from abusing their children. Not only should we get tests, we also should check whether the parents can support their children. Do they have a job? Own a house? If either of these questions is 'no', they should not be allowed to get a child until they do. Again, this is to ensure child welfare. Thirdly, we should check for their criminal background. Some past offences like (child) rape and murder are not very compatible with proper parenting, in my opinion. Such people are also excluded.
Of course I'm not saying we will prevent all child-abuse this way. But it will help a lot. I do want that the procedure is standardized, and all decisions accessible, so that we don't create powerful bureaucrats.
FINAL REMARKS
First, I want to say that without the sterilization part, the artificial human breeding is still a good idea. We'll get healthier and smarter people, which is a big thing already. And with proper education human population growth is already reduced a lot. And before we can control human population growth, we need societies that are designed to minimize corruption. Baby breeding should not become a big money-making business. The current world is not ready for it yet.